HRGM_Genome_1640 - 1 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

c00002_HRGM_G.. (original name was: HRGM_Genome_1640_2) (Genus species)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS,T1PKS	452,241	506,676

Region	Type	From	To	Most similar known cluster	Similarity
Region 2.1	NRPS,T1PKS	452,241	506,676

No secondary metabolite regions were found in these records:: c00001_HRGM_G.. (original name was: HRGM_Genome_1640_1) (Genus species); c00003_HRGM_G.. (original name was: HRGM_Genome_1640_3) (Genus species); c00004_HRGM_G.. (original name was: HRGM_Genome_1640_4) (Genus species); c00005_HRGM_G.. (original name was: HRGM_Genome_1640_5) (Genus species); c00006_HRGM_G.. (original name was: HRGM_Genome_1640_6) (Genus species); c00007_HRGM_G.. (original name was: HRGM_Genome_1640_7) (Genus species); c00008_HRGM_G.. (original name was: HRGM_Genome_1640_8) (Genus species); c00009_HRGM_G.. (original name was: HRGM_Genome_1640_9) (Genus species); c00010_HRGM_G.. (original name was: HRGM_Genome_1640_10) (Genus species); c00011_HRGM_G.. (original name was: HRGM_Genome_1640_11) (Genus species); c00012_HRGM_G.. (original name was: HRGM_Genome_1640_12) (Genus species); c00013_HRGM_G.. (original name was: HRGM_Genome_1640_13) (Genus species); c00014_HRGM_G.. (original name was: HRGM_Genome_1640_14) (Genus species); c00015_HRGM_G.. (original name was: HRGM_Genome_1640_15) (Genus species); c00016_HRGM_G.. (original name was: HRGM_Genome_1640_16) (Genus species); c00017_HRGM_G.. (original name was: HRGM_Genome_1640_17) (Genus species); c00018_HRGM_G.. (original name was: HRGM_Genome_1640_18) (Genus species); c00019_HRGM_G.. (original name was: HRGM_Genome_1640_19) (Genus species); c00020_HRGM_G.. (original name was: HRGM_Genome_1640_20) (Genus species); c00021_HRGM_G.. (original name was: HRGM_Genome_1640_21) (Genus species); c00022_HRGM_G.. (original name was: HRGM_Genome_1640_22) (Genus species)

Compact view

c00002_HRGM_G.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 452,241 - 506,676 nt. (total: 54,436 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 452240 - 506676:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (ohmal) + (cys) + (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

HRGM_Genome_1640_CDS_00980

Search NORINE for peptide: strict or relaxed

AMP-binding (32..440): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: dhb, sal
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVisK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 80% (moderate)

HRGM_Genome_1640_CDS_00981

Search NORINE for peptide: strict or relaxed

AMP-binding (549..946): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

HRGM_Genome_1640_CDS_00982

PKS_AT (518..795): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 82.4
Methoxymalonyl-CoA: 51.7
Methylmalonyl-CoA: 47.0
inactive: 38.8
Propionyl-CoA: 25.1
fatty_acid: 24.9
Ethylmalonyl-CoA: 23.7
Benzoyl-CoA: 21.1
Isobutyryl-CoA: 16.2
trans-1,2-CPDA: 8.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

HRGM_Genome_1640_CDS_00983

Search NORINE for peptide: strict or relaxed

AMP-binding (499..898): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

HRGM_Genome_1640_CDS_00984

Search NORINE for peptide: strict or relaxed

AMP-binding (2099..2496): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)